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PSORIASIS:
Pink Papules/ Plaques/ Pinpoint bleeding (Auspitz sign)/ Physical injury (Koebner phenomenon)/ Pain
Silver Scale/ Sharp margins
Onycholysis/ Oil spots
Rete Ridges with Regular elongation
Itching
Arthritis/ Abscess (Munro)
Stratum corneum with nuclei, neutrophils
Immunologic
Stratum granulosum absent/ Stratum Spinosum thickening
HANG PC
HCTZ (hydrochlorothiazide)
Antimalarials / Allopurinol
Naprosen/NSAIDS
Gold
Penicillamine / Phenothiazines
Captopril / ACEI / Ca Channel blockers
"It is generalized and no area of skin is SPARED"
- Sunlight
- Pregnancy
- Addison's disease
- Renal failure
- Excess of iron (hemochromatosis)
- Drugs (Eg. Busulfan)
HHAPPPPPy
Herpes - HSV, VZV, CMV (blueberry muffin baby), Roseola (HHV6 and 7 - half a dozen roses), Kaposi's (HHV8), possibly PR
Hepadna - Hepatitis B
Adeno
Papilloma= HPV. 6,11,16,18 in Gardasil. 6,11 = warts. 16,18 = dysplasia; E6-p53; E7-Retinoblastoma
Polyoma = JC John Cunningham Virus - PML - why Efalizumab taken off market; Merkel Cell = CK20 - paranuclear dot
Papova = old name that includes Papilloma and Polyoma
Pox = Molluscum, Smallpox, Vaccinia; (Orf = parapox)
Parvo B19 = slapped cheeks, lacy rash, anemia, joint pain in adults. Bad in pregnancy, sickle cell.
6 A's
Asthenia
Areola pigmentation
Arterial hypotension
Alimentary abnormality (anorexia, acute abdomen mimic)
Anxiety
Axillary and pubic hair
CHAPED
Contact Dermatitis
Hypertrophic Sal. Gland (Cheilitis glandularis)
Actinic Cheilitis
Photosensitivity
Exfoliative Cheilitis and factitial
Drug (cis Retinoic Acid)
HERB MEND
Hepatic disease
Endocrinopathy
Renal disease
Blood dyscrasias
Malignancy
External infestations
Neurosis
Drug
"A, B, C, D.........G"
- Asymptomatic lesion
- Bubo
- Chlamydia Trachomatis (causative agent)
- Doxycycline (drug of choice)
- Esthiomene
- Frei's test
- Groove sign
"CAFE SPOT" :
- Café au lait spots
- Axillary freckling
- Fibromatosis
- Eye- Lisch nodules
- Skeletal bowing
- Positive family history
- Optic Tumor
The 10 "I" s of antigen encounter in hypersensitive utricaria
INGESTION
INHALATION
INSTILLATION
INJECTION
INSERTION
INSECTBITE
INFESTATION
INFECTION
INFUSION
INUNCTION(contact)
